I would suggest the Scenic Drive in the San Juan Mountains. COLORADO. Various roads running through the western San Juan Mountains allow for a scenic loop drive of about 245 miles, visiting all major towns and passing imposing mountain scenery all the way: CO 145 north from Cortez to Telluride, CO 62 east to Ridgway then US 550 south through Ouray, Silverton and Durango, with the loop completed by US 60 back to Cortez, past the entrance to Mesa Verde National Park. The loop, known as the San Juan Skyway, can be driven in half a day but it is well worth spending at least one night en route, either in one of the small towns or camping free in the surrounding national forest. Dolores, Telluride, Ouray, Silverton and Durango are all towns that you will pass through on this ride.
Google: Scenic Drive in the San Juan Mountains. It will explaine every town along the way.
I took this trip a long time ago in a four wheeler and dreamed of the day that i would have my bike to make the same ride. Havnt done it yet but it is on top of my to ride list.
Also it is near the four corners area which will lead you to Northern Arizona. The Grand Canyon and through to Route 66.
In any case enjoy your trip !