Like DD said. Watch the corners. The worst will have "SLO" painted in the road before you get to them. Don't let the guys on the crotch rockets try to push you. They tend to just appear from nowhere in your mirrors. Flag them by and enjoy the ride. Tennessee Troopers work the road heavy on the weekends. Do the speed limit and they won't bother you. Remember, its not a race, its a ride.
Stop by Lynn's Place in Robbinsville for a steak. Good stuff! If you have time, make a trip to Highlands. Great road and some beautiful waterfalls right off the road. 28 to Franklin and 64 to Highlands.
Be safe!!